Local hormone

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Local hormones, by one definition, are biologically active polypeptides that are secreted by nerve cells and gland cells and act in a paracrine fashion but also enter the circulation. By another definition, local hormones are any hormones acting in a paracrine, autocrine, and/or intracrine manner.

Contents

Classification

According to structural and functional similarity, many local hormones fall into either the gastrin or the secretin family.

Gastrin family

  1. Gastrin
  2. Cholecystokinin (CCK)

Secretin family

  1. Secretin
  2. Glucagon
  3. Glicentin (GLI)
  4. Vaso-active intestinal polypeptide (VIP)
  5. Gastric inhibitory polypeptide (GIP)

Others

  1. Motilin
  2. Neurotensin
  3. Substance P
  4. Somatostatin
  5. Bombesin
  6. Serotonin
Signaling pathways
Agents
By location
Other concepts
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)